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Shooting the tonal range of an image
In digital photography, the _tonal range_ of an image is the range of shadows, mids, and highlights in the image. Figure 10-7 shows a series of photos that were captured from the same image, but the exposure changed from a light to a dark image with each consecutive exposure. Not all images, whether captured digitally or with a film camera, can be shot at all levels of exposure; you must choose a level that gives you the best image quality based on lighting and the scene.
FIGURE 10-7: The
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Losing a crucial application
Having worked with Photoshop for 20 years, I’m used to having Photoshop as part of my computer environment and I prefer the way it works to Elements.
Over the years, I’ve found myself dealing with ads, which I’ve banned from my WordPress admin area on a couple of my websites. I had to change the “I’m a webmaster, so I know better” attitude. I’ve had to learn to be tolerant of ads, because I am: users pay for the content I produce.
But I found myself more and more intolerant of ads appearing on my blog posts. A recent security patch caused a big debate about the security risks of digital ads. I’ve also moved to a better template, with fewer ads.
My experience with Elements
I’ve been using Photoshop Elements for about 3 months, but I’ve been making the jump from Photoshop CS4 to Photoshop CC, in fact, and it’s been an interesting experience!
For some of us, you can get away with not knowing all the features of this program, but for others, they might be a must-have. Elements is relatively new and hasn’t had the time to be fully fleshed out.
1. The user interface
This is the first thing that I noticed. The Elements interface is extremely simple and clean. I’ve never used a program that has a minimalist UI. It feels powerful and fast. It doesn’t get in the way. It’s fluid and well-organized, yet it’s easy to navigate.
It wasn’t too long before I realized that I felt like I could put this app on a smartphone, to use, and it would be just as powerful and fast.
2. The learning curve
Elements has a bit of a learning curve, as do all programs. The learning curve comes from using the tool, which has a handful of different options, each with many options and numerous icons.
You have to learn when to use what tool, so I found myself having to Google more, which took time. It also gave me the opportunity to learn some of the names of the tools.
My advice: I would keep a camera with me all the time. I would snap pictures of specific things that are bothering me. You can use these pictures as reminders of what each tool is used for. Sometimes, when I’m in the studio, I’ll Google the name of a
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If you’re a longtime LEGO fan, you know that the company is best known for its little plastic bricks. But if you’ve ever wondered about the company’s very famous plastic brick – the one with a LEGO on its front – you’d be surprised to know that it actually wasn’t made by LEGO at all.
A similar iteration of the iconic brick first appeared in 1976 as part of a film called The Five Man Army, but it took a bit of time to catch on. More than 40 years later, the iconic LEGO brick is still going strong – and not just because some people like to build with them.
In celebration of LEGO’s anniversary, take a look at this slideshow to see why the plastic brick was so damn important in the first place. and 01) **b** Breast image before (upper row) and after (lower row) the preprocessing procedure, **c** rectum image before (upper row) and after (lower row) the preprocessing procedure, and **d** bladder image before (upper row) and after (lower row) the preprocessing procedure. The PVCI improved the contrast, particularly in the bladder (see the arrows in the second row of **d**)
The proposed PVCI is also computationally simple and could be potentially useful for real-time applications. As shown in Fig. [11](#Fig11){ref-type=”fig”}, each PVCI frame takes 0.28 s to compute at a rate of 20 frames/s (thus, two or more frames are acquired within a second), which is typically faster than the currently available image processing solutions and has a computational complexity only approximately one-fifth as high as that of the STC technique.Fig. 11The time and the computational complexity of the proposed PVCI in comparison with the two control algorithms based on the reference standardization and PCA and the methodology in \[[@CR16]\]
Conclusions {#Sec16}
===========
In this study, we presented a PVCI method for high-contrast image enhancement. Inspired by the well-known CIE coordinated colorimetry, the PVCI combines the color transformation and the contrast enhancement in a simple and easy way. We further introduced a high-pass filtering based on Gaussian kernels to overcome the Gaussian blurring in input images for the intensity image and to preserve small-scale detail in regions rich in contrast. This high-pass filtering is based on a convex transformation
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Monoharringtonine is a typical mitotic inhibitor, which is a drug isolated from a plant, Cephalotaxus harringtonia. It has been successfully developed to treat acute myeloid leukemia (AML). However, the mechanism of monoharringtonine is still unclear. The objective of this study was to investigate the potential role of mitochondrial dysfunction in monoharringtonine-induced AML apoptosis. The results showed that monoharringtonine significantly inhibited the proliferation of AML cells. The cell cycle was arrested at the G2/M phase after 24 h of treatment. Cells were also recruited to an early apoptotic state as well as a late apoptotic state at 48 h. Reactive oxygen species, reactive nitrogen species, ATP and mitochondrial membrane potential were reduced, while mitochondrial release of cytochrome c and activation of caspase-9, caspase-3 and caspase-8 were observed after 24 h of treatment. More importantly, the ratio of Bax/Bcl-2 and the activity of apoptosis-inducing factor were elevated. All these events are typical of mitochondria-associated intrinsic apoptosis. These results indicated that monoharringtonine induced AML apoptosis through mitochondrial dysfunction, suggesting that mitochondrial dysfunction might be associated with the antitumor effect of monoharringtonine.Dioceses for service areas outside the National Transport Authority (NTA) regional service boundary will be allocated a proportion of the Government-funded NTA services based on geographic needs.
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